Publications

#28

Editorial: Next generation in vitro models to study chronic pulmonary diseases, volume II

Guo T.J.F , Osei E.T., Faiz. A., Pouwels S.D. (2025)

DOI: 10.3389/fmed.2025.1683514

#27

Dynamic mechanical stimulation of alveolar epithelial-fibroblast models using the Flexcell tension system to study of lung disease mechanisms

Al Yazeedi S, Guo T.J.F, Joban S., Abokor A.F., Baher J.Z., Yee L., Cheung C., Sin D.D., and Osei E.T. (2025)

DOI: 10.3389/fmed.2025.1552803

#26

Exploring Multi-Organ Crosstalk via the TissUse HUMIMIC Chip System: Lessons Learnt So Far

Abokor F.A., Yazeedi SAl., Baher J.Z., Cheung C., Don D.D. Osei E.T. (2025)

DOI: 10.1002/bit.70031

#25

Establishing a 3D Vascularized Tri-Culture Model of the Human Airways via a Digital Light Processing Bioprinter

Phogat S., Guo T. J. F., Thiam F. Osei, E.T. (2025)

DOI: 10.1002/bit.29013

#24

Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair

Usman K., Fouadi M., Nwozor K.O., Aminazadeh F., Nair P., Luo H., Sin D.D., Osei, E.T., and Hackett T.L. (2024)

DOI: 10.1016/j.matbio.2024.06.007

#23

The effect of the Mechanodynamic lung environment on fibroblast phenotype via the Flexcell. BMC Pulmonary Medicine

Al Yazeedi S., Abokor A.F, Brussow J., Thiam F., Phogat S., Osei E.T.(2024)

DOI: 10.1186/s12890-024-03167-7

#22

In vitro co-culture studies and the crucial role of fibroblast-immune cell crosstalk in IPF pathogenesis

Thiam F., Phogat S., Abokor F., Osei E.T. (2023)

DOI: 10.1186/s12931-023-02608-x

#21

Next generation in vitro models to study chronic pulmonary diseases

Thiam F., Faiz A., Pouwels S.D. and Osei E.T. (2023)

DOI: 10.3389/fmed.2023.1338939

#20

3D in vitro hydrogel models to study the human lung extracellular matrix and fibroblast function

Phogat S., Thiam F., Al Yazeedi S., Abokor F., and Osei E. T. (2023)

DOI: 10.1186/s12931-023-02548-6

#19

Epithelial-fibroblast interactions in IPF: lessons from in vitro co-culture studies

Brussow J., Feng K., Thiam F. and Osei E.T. (2023)

DOI: 10.1016/j.diff.2023.09.001

#18

The contribution of reticular basement membrane proteins to basal airway epithelial attachment, spreading and barrier formation: implications for airway remodeling in asthma

Hsieh A., Yang C. X., Al-Fouadi M., Nwozor, K. O., Osei E.T. and Hackett T.L. (2023)

DOI: 10.3389/fmed.2023.1214130

#17

Understanding fibroblast-immune cell interactions via co-culture models and their role in asthma pathogenesis

Thiam F., Al Yazeedi S., Feng K., Phogat S., Demirsoy E., Brussow J., Abokor F.A., and Osei E.T. (2023)

DOI: 10.1371/journal.pone.0229278

#16

Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma

Tam A., Osei E.T., Cheug C.Y., Hughes M., Yang C.X., McNagny K.M., Dorscheid D. R., Singhera K. G., Hallstrand T. S., Warner S., Hogg J.C., Hackett T.L., Lim C.J. and Sin D.D. (2022)

DOI: 10.3390/cells11193016

#15

Canadian lung tissue biobank with associated clinical data supporting respiratory research for four decades

Sutherland D.P., Vasilescu D.M., Osei E.T., Coxson N.E., Yang C.X., Booth S., Coxson H.O., Elliot W.M., Paré P.D., Hogg J.C, and Hackett T.L. (2022)

DOI: 10.1080/24745332.2021.1878007

#14

The Role of the Dynamic Lung Extracellular Matrix Environment on Fibroblast Morphology and Inflammation

Hackett T.L, Vriesde N.R.T.F, Al-Fouadi M, Mostaco-Guidolin L, Maftoun D, Hsieh A, Coxson N, Usman K, Sin D.D, Booth S, Osei E.T. (2022)

DOI: 10.3390/cells11020185

#13

Modeling Extracellular Matrix-Cell Interactions in Lung Repair and Chronic Disease

Hackett T.-L and Osei E.T. (2021)

DOI: 10.3390/cells10082145

#12

Second harmonic generation imaging of collagen scaffolds within the alveolar ducts of healthy and emphysematous mouse lungs

Mostaco-Guidolin L., Loube J., Barlow A., Osei E.T., Vasilescu M.D., Hsieh A., AL-Fouadi M., Scott A., Mitzner W. and Hackett T.L. (2021)

DOI: 10.1007/s00418-020-01959-6

#11

Epithelial-mesenchymal crosstalk in COPD: An update from in vitro model studies

Osei E.T. and Hackett T.L. (2020)

DOI: 10.1016/j.biocel.2020.105775

#10

What Have In Vitro Co-Culture Models Taught Us about the Contribution of Epithelial-Mesenchymal Interactions to Airway Inflammation and Remodeling in Asthma?

Osei E.T., Booth S., Hackett T.L. (2020)

DOI: 10.3390/cells9071694

#9

Epithelial-interleukin-1 inhibits collagen formation by airway fibroblasts: Implications for asthma

Osei E.T., Mostaço-Guidolin L.B., Hsieh A., Wang M., Warner S., AL-Fouadi M., Cole D.J., Maksym G.N., Timens W., Hallstrand T., Brandsma C.A., Heijink I.H., and Hackett T.L. (2020)

DOI: 10.1038/s41598-020-65567-z

#8

Super resolution measurement of collagen fibers in biological samples: Validation of a commercial solution for multiphoton microscopy

Barlow M.A., Mostaço-Guidolin L.B., Osei E.T., Booth S., and Hackett T.-L. (2020)

DOI: 10.1371/journal.pone.0229278

#7

Current perspectives on the role of interleukin-1 signalling in the pathogenesis of asthma and COPD

Osei E.T., Brandsma C-A, Timens W, Heijink I.H. and Hackett T-L. (2019)

DOI:

#6

Defective Fibrillar Collagen Organization by Fibroblasts Contributes to Airway Remodeling in Asthma

Osei E.T., Mostaco-Guidolin L.B, Ullah J., Hajimohammadi S., Li X., Li V., AL-Fouadi M., Yang Y., Shaheen, F., Chu F., Cole D.J., Brandsma C-A., Heijink I.H., Maksym G.N., Walker D. and Hackett TL (2019)

DOI: 10.1164/rccm.201810-1855OC

#5

De rol van epitheel-fibroblast-communicatie in astma en COPD

Osei E.T. (2018)

#4

The role of epithelial-fibroblast communication in asthma and COPD

Osei E.T. (2017)

DOI: 10.14288/1.0355543

#3

miR-146a-5p plays an essential role in the aberrant epithelial–fibroblast cross-talk in COPD

Osei E.T., Florez-Sampedro L, Tasena H, Faiz A, Noordhoek JA, Timens W, Postma DS, Hackett TL, Heijink IH, Brandsma CA. (2017)

DOI: 10.1183/13993003.02538-2016

#2

Interleukin-1α drives the dysfunctional cross-talk of the airway epithelium and lung fibroblasts in COPD

Osei E.T., Noordhoek J.A., Hackett T.L., Spanjer A.I.R., Postma S.D., Timens, W., Brandsma C-A and Heijink I.H. (2016)

DOI: 10.1183/13993003.01911-2015

#1

Unravelling the complexity of COPD by microRNAs: it's a small world after all | European Respiratory Society

OSEI LAB

Publications

#28

Editorial: Next generation in vitro models to study chronic pulmonary diseases, volume II

​​ Guo T.J.F , Osei E.T., Faiz. A., Pouwels S.D. (2025)

DOI: 10.3389/fmed.2025.1683514

​ ​

#27

Al Yazeedi S, Guo T.J.F, Joban S., Abokor A.F., Baher J.Z., Yee L., Cheung C., Sin D.D., and Osei E.T. (2025)

​

DOI: 10.3389/fmed.2025.1552803​

#26

Abokor F.A., Yazeedi SAl., Baher J.Z., Cheung C., Don D.D. Osei E.T. (2025)

​

DOI: 10.1002/bit.70031​

#25

Establishing a 3D Vascularized Tri-Culture Model of the Human Airways via a Digital Light Processing Bioprinter

​​ Phogat S., Guo T. J. F., Thiam F. Osei, E.T. (2025) DOI: 10.1002/bit.29013 ​

#24

Usman K., Fouadi M., Nwozor K.O., Aminazadeh F., Nair P., Luo H., Sin D.D., Osei, E.T., and Hackett T.L. (2024)

DOI: 10.1016/j.matbio.2024.06.007​

#23

​​ ​

#22

Thiam F., Phogat S., Abokor F., Osei E.T. (2023)​

​

DOI: 10.1186/s12931-023-02608-x

#21

Thiam F., Faiz A., Pouwels S.D. and Osei E.T. (2023)​

​

DOI: 10.3389/fmed.2023.1338939

#20

Phogat S., Thiam F., Al Yazeedi S., Abokor F., and Osei E. T. (2023)​

​

DOI: 10.1186/s12931-023-02548-6

#19

Brussow J., Feng K., Thiam F. and Osei E.T. (2023)​

​

DOI: 10.1016/j.diff.2023.09.001

#18

Hsieh A., Yang C. X., Al-Fouadi M., Nwozor, K. O., Osei E.T. and Hackett T.L. (2023)​

​

DOI: 10.3389/fmed.2023.1214130

#17

Thiam F., Al Yazeedi S., Feng K., Phogat S., Demirsoy E., Brussow J., Abokor F.A., and Osei E.T. (2023)

​

DOI: 10.1371/journal.pone.0229278

​

#16

Tam A., Osei E.T., Cheug C.Y., Hughes M., Yang C.X., McNagny K.M., Dorscheid D. R., Singhera K. G., Hallstrand T. S., Warner S., Hogg J.C., Hackett T.L., Lim C.J. and Sin D.D. (2022)

​

DOI: 10.3390/cells11193016

​

#15

Sutherland D.P., Vasilescu D.M., Osei E.T., Coxson N.E., Yang C.X., Booth S., Coxson H.O., Elliot W.M., Paré P.D., Hogg J.C, and Hackett T.L. (2022)

​

DOI: 10.1080/24745332.2021.1878007

#14

Hackett T.L, Vriesde N.R.T.F, Al-Fouadi M, Mostaco-Guidolin L, Maftoun D, Hsieh A, Coxson N, Usman K, Sin D.D, Booth S, Osei E.T. (2022)

​

DOI: 10.3390/cells11020185

#13

Hackett T.-L and Osei E.T. (2021)

​

DOI: 10.3390/cells10082145

#12

Mostaco-Guidolin L., Loube J., Barlow A., Osei E.T., Vasilescu M.D., Hsieh A., AL-Fouadi M., Scott A., Mitzner W. and Hackett T.L. (2021)

​

DOI: 10.1007/s00418-020-01959-6

#11

Osei E.T. and Hackett T.L. (2020)

​

DOI: 10.1016/j.biocel.2020.105775

#10

Osei E.T., Booth S., Hackett T.L. (2020)

​

DOI: 10.3390/cells9071694

#9

Osei E.T., Mostaço-Guidolin L.B., Hsieh A., Wang M., Warner S., AL-Fouadi M., Cole D.J., Maksym G.N., Timens W., Hallstrand T., Brandsma C.A., Heijink I.H., and Hackett T.L. (2020)

​

Guo T.J.F , Osei E.T., Faiz. A., Pouwels S.D. (2025)

DOI: 10.3389/fmed.2025.1552803

DOI: 10.1002/bit.70031

Phogat S., Guo T. J. F., Thiam F. Osei, E.T. (2025)

DOI: 10.1002/bit.29013

DOI: 10.1016/j.matbio.2024.06.007

Thiam F., Phogat S., Abokor F., Osei E.T. (2023)

Thiam F., Faiz A., Pouwels S.D. and Osei E.T. (2023)

Phogat S., Thiam F., Al Yazeedi S., Abokor F., and Osei E. T. (2023)

Brussow J., Feng K., Thiam F. and Osei E.T. (2023)

Hsieh A., Yang C. X., Al-Fouadi M., Nwozor, K. O., Osei E.T. and Hackett T.L. (2023)

Osei E.T. (2018)

Osei E.T. (2017)